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Prion Protein Monoclonal Antibody - 2G11
Antibodies - Monoclonal Antibodies

ize: 200 µg
서한형 대리
010-8832-6303

제품소개

Territorial Availability: Available worldwide directly through Bertin or your local distributor
Synonyms:
  • Prion Protein Monoclonal Antibody - 2G11
Correlated keywords:
  • proteins
  • mad
  • cow
  • diseases
  • bovine
  • spongiform
  • encephalopathy
  • scrapie
Show less...
  • Creutzfeldt-jakob
  • neurodegeneration
  • antibodies
  • antisera
  • antiserum
  • neurochemistry
  • neuroscience
  • spi-bio
  • spibio
  • A03200
Product Overview:
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease.
This antibody recognises the 149-161 peptide motif on the ovine sequence that is EDRYYRENMYRYP.

Size200 µg
ShippingDry Ice
HostMouse
AntigenThis anti-Prion Protein Monoclonal Antibody was raised against a synthetic peptide (146-182) of the ovine PrP peptide.
Clone2G11
IsotypeIgG2a
Application(s)

Reconstitute the content of the vial in 1 mL of water.

IHC for sheep PrPres without PK treatment

For immunohistochemistry, the optimal working dilution must be determined empirically (currently between 0.1 and 1 µg/mL). Mab 2G11 binds to the partially denatured or oxidized normal prion protein in vitro and as such is an indicator (by lack of signal) of preservation of the native state.

Specificity
Application MediaReconstitute the content of the vial in 1 mL of water.
Formulationlyophilized IgG with BSA
Custom Code3822000000
UNSPSC code12352203


Andreoletti O., Berthon P., Marc D., Sarradin P., Grosclaude J., Van Keulen L., Schelcher F., Elsen J-M., and Lantier F. (2000). Early accumulation of PrPSc in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natural scrapie J.Gen Virol, 81, 3115-3126

 

주문정보

CAT.No 품명 규격 비고
A03225 Prion Protein Monoclonal Antibody - 2G11 200 µg Antibodies - Monoclonal Antibodies